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butabarbital will reduce the level or influence of nifedipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Mysterious.butabarbital will minimize the level or effect of glecaprevir/pibrentasvir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.butabarbital will lower the extent or outcome of prednisolone by inf